Protein Engineering, Vol 10, 1-6, Copyright © 1997 by Oxford University Press
H Nielsen, J Engelbrecht, S Brunak and G von Heijne
We have developed a new method for the identification of signal peptides
and their cleavage sites based on neural networks trained on separate sets
of prokaryotic and eukaryotic sequence. The method performs significantly
better than previous prediction schemes and can easily be applied on
genome-wide data sets. Discrimination between cleaved signal peptides and
uncleaved N-terminal signal-anchor sequences is also possible, though with
lower precision. Predictions can be made on a publicly available WWW
server.
ARTICLES
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
Department of Chemistry, Technical University of Denmark, Lyngby, Denmark.
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C. Hamsten, J. Westberg, G. Bolske, R. Ayling, M. Uhlen, and A. Persson Expression and immunogenicity of six putative variable surface proteins in Mycoplasma mycoides subsp. mycoides SC Microbiology, February 1, 2008; 154(2): 539 - 549. [Abstract] [Full Text] [PDF] |
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N. J. Nadeau, F. Minvielle, S. Ito, M. Inoue-Murayama, D. Gourichon, S. A. Follett, T. Burke, and N. I. Mundy Characterization of Japanese Quail yellow as a Genomic Deletion Upstream of the Avian Homolog of the Mammalian ASIP (agouti) Gene Genetics, February 1, 2008; 178(2): 777 - 786. [Abstract] [Full Text] [PDF] |
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M. Leroch, H. E. Neuhaus, S. Kirchberger, S. Zimmermann, M. Melzer, J. Gerhold, and J. Tjaden Identification of a Novel Adenine Nucleotide Transporter in the Endoplasmic Reticulum of Arabidopsis PLANT CELL, February 1, 2008; 20(2): 438 - 451. [Abstract] [Full Text] [PDF] |
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M. D. Dean, J. M. Good, and M. W. Nachman Adaptive Evolution of Proteins Secreted during Sperm Maturation: An Analysis of the Mouse Epididymal Transcriptome Mol. Biol. Evol., February 1, 2008; 25(2): 383 - 392. [Abstract] [Full Text] [PDF] |
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R. Iijima, T. Kunieda, S. Yamaguchi, H. Kamigaki, I. Fujii-Taira, K. Sekimizu, T. Kubo, S. Natori, and K. J. Homma The Extracellular Adenosine Deaminase Growth Factor, ADGF/CECR1, Plays a Role in Xenopus Embryogenesis via the Adenosine/P1 Receptor J. Biol. Chem., January 25, 2008; 283(4): 2255 - 2264. [Abstract] [Full Text] [PDF] |
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A. M. Pollard, K. N. Onatolu, L. Hiller, K. Haldar, and L. J. Knoll Highly Polymorphic Family of Glycosylphosphatidylinositol-Anchored Surface Antigens with Evidence of Developmental Regulation in Toxoplasma gondii Infect. Immun., January 1, 2008; 76(1): 103 - 110. [Abstract] [Full Text] [PDF] |
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Y. Umemoto, R. Onishi, and T. Araki Cloning of a Novel Gene Encoding -1,3-Xylosidase from a Marine Bacterium, Vibrio sp. Strain XY-214, and Characterization of the Gene Product Appl. Envir. Microbiol., January 1, 2008; 74(1): 305 - 308. [Abstract] [Full Text] [PDF] |
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H. Nakai, S. Tanizawa, T. Ito, K. Kamiya, Y.-M. Kim, T. Yamamoto, K. Matsubara, M. Sakai, H. Sato, T. Imbe, et al. Function-unknown Glycoside Hydrolase Family 31 Proteins, mRNAs of which were Expressed in Rice Ripening and Germinating Stages, are {alpha}-Glucosidase and {alpha}-Xylosidase J. Biochem., October 1, 2007; 142(4): 491 - 500. [Abstract] [Full Text] [PDF] |
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N. Gupta, S. Tanner, N. Jaitly, J. N. Adkins, M. Lipton, R. Edwards, M. Romine, A. Osterman, V. Bafna, R. D. Smith, et al. Whole proteome analysis of post-translational modifications: Applications of mass-spectrometry for proteogenomic annotation Genome Res., September 1, 2007; 17(9): 1362 - 1377. [Abstract] [Full Text] [PDF] |
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J. J. Reina, C. Guerrero, and A. Heredia Isolation, characterization, and localization of AgaSGNH cDNA: a new SGNH-motif plant hydrolase specific to Agave americana L. leaf epidermis J. Exp. Bot., August 1, 2007; 58(11): 2717 - 2731. [Abstract] [Full Text] [PDF] |
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K. Hara, R. Kajita, K. U. Torii, D. C. Bergmann, and T. Kakimoto The secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule Genes & Dev., July 15, 2007; 21(14): 1720 - 1725. [Abstract] [Full Text] [PDF] |
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