Protein Engineering, Vol 11, 249-251, Copyright © 1998 by Oxford University Press
MM Gromiha and S Selvaraj
Information about the secondary structure of a protein can be helpful in
understanding its native folded state. In previous work, it was shown that
the medium-range interactions predominate in all-alpha class and the
long-range interactions predominate in all-beta class proteins. Based on
this, in this work the performance of several structure prediction methods
in different structural classes of globular proteins was analyzed. It was
found that all the methods predict the secondary structures of all-alpha
proteins more accurately than other classes.
ARTICLES
Protein secondary structure prediction in different structural classes
Tsukuba Life Science Center, Institute of Physical and Chemical Research (RIKEN), Ibaraki, Japan. gromiha@rtc.riken.go.jp
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