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Protein Engineering, Vol. 15, No. 10, 771-774, October 2002
© 2002 Oxford University Press

COMMUNICATION

Sequence relationships in the legume lectin fold and other jelly rolls

A. Williams and D.R. Westhead1

School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK

Distant sequence relationships in proteins containing the ß jelly-roll fold were investigated using sensitive sequence comparison methods, including PSI-BLAST and Hidden Markov Models. A relationship was identified between the rmlC-like and phosphomannose isomerase SCOP (version 1.53) superfamilies, which were merged in the most recent SCOP release. No other distant sequence relationships linking jelly roll superfamilies were found.


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