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Protein Engineering Design and Selection 2009 22(3):221-224; doi:10.1093/protein/gzp003
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© The Author 2009. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

This article appears in the following Protein Engineering issue: Antibody Special Issue [View the issue table of contents]

Short communications

Data standards for minimum information collection for antibody therapy experiments

M. Yong1, B. Tolner, S. Nagl, R.B. Pedley, K. Chester, A.J. Green, A. Mayer, S. Sharma and R. Begent

UCL Cancer Institute, University College London, Paul O’Gorman Building, London WC1E 6BT, UK

1 To whom correspondence should be addressed. E-mail: m.yong{at}ucl.ac.uk

Research groups developing antibody therapies generate diverse data sets; the value of these sets would be compounded when shared or amalgamated. A complete amalgamation of diverse data sets requires data standards for information collection during experiments. We propose to define elements of the data standards in the form of common data elements (CDEs) in order to clarify each experiment’s targets and data values. We have created a set of core information elements which we suggest should be collected from antibody therapy experiments. We propose these as a basis for community consultation with a view to defining a set of data standards which can be developed under the auspices of the Antibody Society.

Keywords: antibody therapy/common data elements/controlled vocabulary/data standards

Received October 1, 2008; revised December 19, 2008; accepted January 5, 2009.


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