Protein Engineering Design and Selection

ARTICLES:

H Nielsen, J Engelbrecht, S Brunak, and G von Heijne

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
Protein Eng. 1997 10: 1-6; doi:10.1093/protein/10.1.1 [Abstract] [PDF] [Request Permissions]  

CM Topham, N Srinivasan, and TL Blundell

Prediction of the stability of protein mutants based on structural environment-dependent amino acid substitution and propensity tables
Protein Eng. 1997 10: 7-21; doi:10.1093/protein/10.1.7 [Abstract] [PDF] [Request Permissions]  

AD Gorse and JE Gready

Molecular dynamics simulations of the docking of substituted N5- deazapterins to dihydrofolate reductase
Protein Eng. 1997 10: 23-30; doi:10.1093/protein/10.1.23 [Abstract] [PDF] [Request Permissions]  

DM van Aalten, PC Jones, M de Sousa, and JB Findlay

Engineering protein mechanics: inhibition of concerted motions of the cellular retinol binding protein by site-directed mutagenesis
Protein Eng. 1997 10: 31-37; doi:10.1093/protein/10.1.31 [Abstract] [PDF] [Request Permissions]  

CO Hewitt, RB Sessions, TR Dafforn, and JJ Holbrook

Protein engineering tests of a homology model of Plasmodium falciparum lactate dehydrogenase
Protein Eng. 1997 10: 39-44; doi:10.1093/protein/10.1.39 [Abstract] [PDF] [Request Permissions]  

C Qu, S Akanuma, H Moriyama, N Tanaka, and T Oshima

A mutation at the interface between domains causes rearrangement of domains in 3-isopropylmalate dehydrogenase
Protein Eng. 1997 10: 45-52; doi:10.1093/protein/10.1.45 [Abstract] [PDF] [Request Permissions]  

JP Schanstra, A Ridder, J Kingma, and DB Janssen

Influence of mutations of Val226 on the catalytic rate of haloalkane dehalogenase
Protein Eng. 1997 10: 53-61; doi:10.1093/protein/10.1.53 [Abstract] [PDF] [Request Permissions]  

MS Warren and SJ Benkovic

Combinatorial manipulation of three key active site residues in glycinamide ribonucleotide transformylase
Protein Eng. 1997 10: 63-68; doi:10.1093/protein/10.1.63 [Abstract] [PDF] [Request Permissions]  

BA Feinberg, X Lo, T Iwamoto, and JM Tomich

Synthetic mutants of Clostridium pasteurianum ferredoxin: open iron sites and testing carboxylate coordination
Protein Eng. 1997 10: 69-75; doi:10.1093/protein/10.1.69 [Abstract] [PDF] [Request Permissions]  

MS Caffrey, PR Gooley, D Zhao, TE Meyer, MA Cusanovich, and NE MacKenzie

The substitution of proline 35 by alanine in Rhodobacter capsulatus cytochrome c2 affects the overall protein stability but not the alkaline transition
Protein Eng. 1997 10: 77-80; doi:10.1093/protein/10.1.77 [Abstract] [PDF] [Request Permissions]  

BB Stoffer, C Dupont, TP Frandsen, J Lehmbeck, and B Svensson

Glucoamylase mutants in the conserved active-site segment Trp170-Tyr175 located at a distance from the site of catalysis
Protein Eng. 1997 10: 81-87; doi:10.1093/protein/10.1.81 [Abstract] [PDF] [Request Permissions]  

MP Deonarain, G Rowlinson-Busza, AJ George, and AA Epenetos

Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting
Protein Eng. 1997 10: 89-98; doi:10.1093/protein/10.1.89 [Abstract] [PDF] [Request Permissions]  

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