Protein Engineering Design and Selection

ARTICLES:

MR Groves, V Dhanaraj, M Badasso, P Nugent, JE Pitts, DJ Hoover, and TL Blundell

A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure
Protein Eng. 1998 11: 833-840; doi:10.1093/protein/11.10.833 [Abstract] [PDF] [Request Permissions]  

JJ Chai, C He, M Li, L Tang, and M Luo

Crystal structure of carboxypeptidase A complexed with an inactivator in two crystal forms
Protein Eng. 1998 11: 841-845; doi:10.1093/protein/11.10.841 [Abstract] [PDF] [Request Permissions]  

MS McAlister, B Davis, M Pfuhl, and PC Driscoll

NMR analysis of the N-terminal SRCR domain of human CD5: engineering of a glycoprotein for superior characteristics in NMR experiments
Protein Eng. 1998 11: 847-853; doi:10.1093/protein/11.10.847 [Abstract] [PDF] [Request Permissions]  

D Milburn, RA Laskowski, and JM Thornton

Sequences annotated by structure: a tool to facilitate the use of structural information in sequence analysis
Protein Eng. 1998 11: 855-859; doi:10.1093/protein/11.10.855 [Abstract] [PDF] [Request Permissions]  

K Zimmermann and JF Gibrat

In unison: regularization of protein secondary structure predictions that makes use of multiple sequence alignments
Protein Eng. 1998 11: 861-865; doi:10.1093/protein/11.10.861 [Abstract] [PDF] [Request Permissions]  

A Karshikoff and R Ladenstein

Proteins from thermophilic and mesophilic organisms essentially do not differ in packing
Protein Eng. 1998 11: 867-872; doi:10.1093/protein/11.10.867 [Abstract] [PDF] [Request Permissions]  

DM van Aalten, WD Hoff, JB Findlay, W Crielaard, and KJ Hellingwerf

Concerted motions in the photoactive yellow protein
Protein Eng. 1998 11: 873-879; doi:10.1093/protein/11.10.873 [Abstract] [PDF] [Request Permissions]  

MA Marti-Renom, JM Mas, B Oliva, E Querol, and FX Aviles

Effects of counter-ions and volume on the simulated dynamics of solvated proteins. Application to the activation domain of procarboxypeptidase B
Protein Eng. 1998 11: 881-890; doi:10.1093/protein/11.10.881 [Abstract] [PDF] [Request Permissions]  

D Cregut, G Drin, JP Liautard, and L Chiche

Hinge-bending motions in annexins: molecular dynamics and essential dynamics of apo-annexin V and of calcium bound annexin V and I
Protein Eng. 1998 11: 891-900; doi:10.1093/protein/11.10.891 [Abstract] [PDF] [Request Permissions]  

J Damborsky, M Bohac, M Prokop, M Kuty, and J Koca

Computational site-directed mutagenesis of haloalkane dehalogenase in position 172
Protein Eng. 1998 11: 901-907; doi:10.1093/protein/11.10.901 [Abstract] [PDF] [Request Permissions]  

B Velikson, P Cohen, M Rholam, JP Rose, BC Wang, and JC Smith

Structural modeling of the pro-ocytocin-neurophysin precursor
Protein Eng. 1998 11: 909-916; doi:10.1093/protein/11.10.909 [Abstract] [PDF] [Request Permissions]  

V Perrier, S Burlacu-Miron, A Boussac, A Meier, and AM Gilles

Metal chelating properties of adenylate kinase from Paracoccus denitrificans
Protein Eng. 1998 11: 917-923; doi:10.1093/protein/11.10.917 [Abstract] [PDF] [Request Permissions]  

G Fiorentino, R Cannio, M Rossi, and S Bartolucci

Decreasing the stability and changing the substrate specificity of the Bacillus stearothermophilus alcohol dehydrogenase by single amino acid replacements
Protein Eng. 1998 11: 925-930; doi:10.1093/protein/11.10.925 [Abstract] [PDF] [Request Permissions]  

P Mukhopadhyay and KB Roy

Protein engineering of BamHI restriction endonuclease: replacement of Cys54 by Ala enhances catalytic activity
Protein Eng. 1998 11: 931-935; doi:10.1093/protein/11.10.931 [Abstract] [PDF] [Request Permissions]  

H Zhu, K Ramnarayan, P Menzel, Y Miao, J Zheng, and S Mong

Identification of two new hydrophobic residues on basic fibroblast growth factor important for fibroblast growth factor receptor binding
Protein Eng. 1998 11: 937-940; doi:10.1093/protein/11.10.937 [Abstract] [PDF] [Request Permissions]  

A Kramer, RD Stigler, T Knaute, B Hoffmann, and J Schneider-Mergener

Stepwise transformation of a cholera toxin and a p24 (HIV-1) epitope into D-peptide analogs
Protein Eng. 1998 11: 941-948; doi:10.1093/protein/11.10.941 [Abstract] [PDF] [Request Permissions]  

M Irnaten, X Gallet, F Festy, G Peranzi, JC Robert, A Thomas-Soumarmon, and R Brasseur

Prediction of epitopes and production of monoclonal antibodies against gastric H,K-ATPase
Protein Eng. 1998 11: 949-955; doi:10.1093/protein/11.10.949 [Abstract] [PDF] [Request Permissions]  

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