Protein Engineering Design and Selection

ARTICLES:

P Whiteman, AK Downing, and PA Handford

NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1
Protein Eng. 1998 11: 957-959; doi:10.1093/protein/11.11.957 [Abstract] [PDF] [Request Permissions]  

D Kihara, T Shimizu, and M Kanehisa

Prediction of membrane proteins based on classification of transmembrane segments
Protein Eng. 1998 11: 961-970; doi:10.1093/protein/11.11.961 [Abstract] [PDF] [Request Permissions]  

CT Zhang, ZS Lin, Z Zhang, and M Yan

Prediction of the helix/strand content of globular proteins based on their primary sequences
Protein Eng. 1998 11: 971-979; doi:10.1093/protein/11.11.971 [Abstract] [PDF] [Request Permissions]  

H Wako and T Yamato

Novel method to detect a motif of local structures in different protein conformations
Protein Eng. 1998 11: 981-990; doi:10.1093/protein/11.11.981 [Abstract] [PDF] [Request Permissions]  

R Samudrala and J Moult

Determinants of side chain conformational preferences in protein structures
Protein Eng. 1998 11: 991-997; doi:10.1093/protein/11.11.991 [Abstract] [PDF] [Request Permissions]  

A Wallqvist, GW Smythers, and DG Covell

A cooperative folding unit in HIV-1 protease. Implications for protein stability and occurrence of drug-induced mutations
Protein Eng. 1998 11: 999-1005; doi:10.1093/protein/11.11.999 [Abstract] [PDF] [Request Permissions]  

A Fengler and W Brandt

Three-dimensional structures of the cysteine proteases cathepsins K and S deduced by knowledge-based modelling and active site characteristics
Protein Eng. 1998 11: 1007-1013; doi:10.1093/protein/11.11.1007 [Abstract] [PDF] [Request Permissions]  

I Gelfand, A Kister, C Kulikowski, and O Stoyanov

Geometric invariant core for the V(L) and V(H) domains of immunoglobulin molecules
Protein Eng. 1998 11: 1015-1025; doi:10.1093/protein/11.11.1015 [Abstract] [PDF] [Request Permissions]  

H Toh, N Kamikawaji, T Tana, T Sasazuki, and S Kuhara

Molecular dynamics simulations of HLA-DR4 (DRB1*0405) complexed with analogue peptide: conformational changes in the putative T-cell receptor binding regions
Protein Eng. 1998 11: 1027-1032; doi:10.1093/protein/11.11.1027 [Abstract] [PDF] [Request Permissions]  

KJ Schleifer and HD Holtje

Molecular modelling investigation of wild-type and the R528H mutated segment IIS4 of human L-type voltage-gated calcium channels
Protein Eng. 1998 11: 1033-1040; doi:10.1093/protein/11.11.1033 [Abstract] [PDF] [Request Permissions]  

MB Murray, DK Tadaki, SR Campion, JA Lamerdin, EH Serpersu, TD Bradrick, and SK Niyogi

Structure-function analysis of a conserved aromatic cluster in the N- terminal domain of human epidermal growth factor
Protein Eng. 1998 11: 1041-1050; doi:10.1093/protein/11.11.1041 [Abstract] [PDF] [Request Permissions]  

K Suzuki, H Hiroaki, D Kohda, and T Tanaka

An isoleucine zipper peptide forms a native-like triple stranded coiled coil in solution
Protein Eng. 1998 11: 1051-1055; doi:10.1093/protein/11.11.1051 [Abstract] [PDF] [Request Permissions]  

AV Grinberg and R Bernhardt

Effect of replacing a conserved proline residue on the function and stability of bovine adrenodoxin
Protein Eng. 1998 11: 1057-1064; doi:10.1093/protein/11.11.1057 [Abstract] [PDF] [Request Permissions]  

TV Burova, Y Choiset, V Tran, and T Haertle

Role of free Cys121 in stabilization of bovine beta-lactoglobulin B
Protein Eng. 1998 11: 1065-1073; doi:10.1093/protein/11.11.1065 [Abstract] [PDF] [Request Permissions]  

M Yamashita, M Toyama, H Ono, I Fujii, N Hirayama, and Y Murooka

Separation of the two reactions, oxidation and isomerization, catalyzed by Streptomyces cholesterol oxidase
Protein Eng. 1998 11: 1075-1081; doi:10.1093/protein/11.11.1075 [Abstract] [PDF] [Request Permissions]  

JH Kanan, SJ Hubbard, SJ Minter, and SG Oliver

Use of fortuitous in vitro mutations in a synthetic Cu-Zn superoxide dismutase gene to illuminate protein structure-function relationships
Protein Eng. 1998 11: 1083-1088; doi:10.1093/protein/11.11.1083 [Abstract] [PDF] [Request Permissions]  

H Kobayashi, H Morioka, O Nikaido, JD Stewart, and E Ohtsuka

The role of surface lysines in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody
Protein Eng. 1998 11: 1089-1092; doi:10.1093/protein/11.11.1089 [Abstract] [PDF] [Request Permissions]  

D Staunton, KR Hudson, and JK Heath

The interactions of the cytokine-binding homology region and immunoglobulin-like domains of gp130 with oncostatin M: implications for receptor complex formation
Protein Eng. 1998 11: 1093-1102; doi:10.1093/protein/11.11.1093 [Abstract] [PDF] [Request Permissions]  

IK Feil, AA Platas, F van den Akker, R Reddy, EA Merritt, DR Storm, and WG Hol

Stepwise transplantation of an active site loop between heat-labile enterotoxins LT-II and LT-I and characterization of the obtained hybrid toxins
Protein Eng. 1998 11: 1103-1109; doi:10.1093/protein/11.11.1103 [Abstract] [PDF] [Request Permissions]  

D Liger, P Nizard, C Gaillard, JC vanderSpek, JR Murphy, B Pitard, and D Gillet

The diphtheria toxin transmembrane domain as a pH sensitive membrane anchor for human interleukin-2 and murine interleukin-3
Protein Eng. 1998 11: 1111-1120; doi:10.1093/protein/11.11.1111 [Abstract] [PDF] [Request Permissions]  

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