Protein Engineering Design and Selection

ARTICLES:

S Fushinobu, K Ito, M Konno, T Wakagi, and H Matsuzawa

Crystallographic and mutational analyses of an extremely acidophilic and acid-stable xylanase: biased distribution of acidic residues and importance of Asp37 for catalysis at low pH
Protein Eng. 1998 11: 1121-1128; doi:10.1093/protein/11.12.1121 [Abstract] [PDF] [Request Permissions]  

R Grandori

Systematic fold recognition analysis of the sequences encoded by the genome of Mycoplasma pneumoniae
Protein Eng. 1998 11: 1129-1135; doi:10.1093/protein/11.12.1129 [Abstract] [PDF] [Request Permissions]  

BV Reddy, S Datta, and S Tiwari

Use of propensities of amino acids to the local structural environments to understand effect of substitution mutations on protein stability
Protein Eng. 1998 11: 1137-1145; doi:10.1093/protein/11.12.1137 [Abstract] [PDF] [Request Permissions]  

C Orrenius, C van Heusden, J van Ruiten, PL Overbeeke, H Kierkels, JA Duine, and JA Jongejan

Simple conformation space search protocols for the evaluation of enantioselectivity of lipases
Protein Eng. 1998 11: 1147-1153; doi:10.1093/protein/11.12.1147 [Abstract] [PDF] [Request Permissions]  

B Eisenhaber, P Bork, and F Eisenhaber

Sequence properties of GPI-anchored proteins near the omega-site: constraints for the polypeptide binding site of the putative transamidase
Protein Eng. 1998 11: 1155-1161; doi:10.1093/protein/11.12.1155 [Abstract] [PDF] [Request Permissions]  

CM Topham, L Mouledous, G Poda, B Maigret, and JC Meunier

Molecular modelling of the ORL1 receptor and its complex with nociceptin
Protein Eng. 1998 11: 1163-1179; doi:10.1093/protein/11.12.1163 [Abstract] [PDF] [Request Permissions]  

PR Gouldson, CR Snell, RP Bywater, C Higgs, and CA Reynolds

Domain swapping in G-protein coupled receptor dimers
Protein Eng. 1998 11: 1181-1193; doi:10.1093/protein/11.12.1181 [Abstract] [PDF] [Request Permissions]  

TA Salminen, DJ Smith, S Jalkanen, and MS Johnson

Structural model of the catalytic domain of an enzyme with cell adhesion activity: human vascular adhesion protein-1 (HVAP-1) D4 domain is an amine oxidase
Protein Eng. 1998 11: 1195-1204; doi:10.1093/protein/11.12.1195 [Abstract] [PDF] [Request Permissions]  

H Takagi, M Yamamoto, I Ohtsu, and S Nakamori

Random mutagenesis into the conserved Gly154 of subtilisin E: isolation and characterization of the revertant enzymes
Protein Eng. 1998 11: 1205-1210; doi:10.1093/protein/11.12.1205 [Abstract] [PDF] [Request Permissions]  

J Van der Schueren, J Robben, and G Volckaert

Misfolding of chloramphenicol acetyltransferase due to carboxy-terminal truncation can be corrected by second-site mutations
Protein Eng. 1998 11: 1211-1217; doi:10.1093/protein/11.12.1211 [Abstract] [PDF] [Request Permissions]  

Y Koga, M Morikawa, M Haruki, H Nakamura, T Imanaka, and S Kanaya

Thermostable glycerol kinase from a hyperthermophilic archaeon: gene cloning and characterization of the recombinant enzyme
Protein Eng. 1998 11: 1219-1227; doi:10.1093/protein/11.12.1219 [Abstract] [PDF] [Request Permissions]  

M Edge, C Forder, J Hennam, I Lee, D Tonge, I Hardern, J Fitton, K Eckersley, S East, A Shufflebotham, D Blakey, and A Slater

Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L- glutamic acid: reversed-polarity mutants
Protein Eng. 1998 11: 1229-1234; doi:10.1093/protein/11.12.1229 [Abstract] [PDF] [Request Permissions]  

CE Sansom, MV Hoang, and AJ Turner

Molecular modelling and site-directed mutagenesis of the active site of endothelin-converting enzyme
Protein Eng. 1998 11: 1235-1241; doi:10.1093/protein/11.12.1235 [Abstract] [PDF] [Request Permissions]  

SP Bottomley and SR Stone

Protein engineering of chimeric Serpins: an investigation into effects of the serpin scaffold and reactive centre loop length
Protein Eng. 1998 11: 1243-1247; doi:10.1093/protein/11.12.1243 [Abstract] [PDF] [Request Permissions]  

M Rahman, Z Jia, BR Gabel, SM Marcovina, and ML Koschinsky

Expression of apolipoprotein(a) kringle IV type 9 in Escherichia coli: demonstration of a specific interaction between kringle IV type 9 and apolipoproteinB-100
Protein Eng. 1998 11: 1249-1256; doi:10.1093/protein/11.12.1249 [Abstract] [PDF] [Request Permissions]  

N Dimasi, A Pasquo, F Martin, S Di Marco, C Steinkuhler, R Cortese, and M Sollazzo

Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein
Protein Eng. 1998 11: 1257-1265; doi:10.1093/protein/11.12.1257 [Abstract] [PDF] [Request Permissions]  

HJ de Haard, B Kazemier, A van der Bent, P Oudshoorn, P Boender, B van Gemen, JW Arends, and HR Hoogenboom

Absolute conservation of residue 6 of immunoglobulin heavy chain variable regions of class IIA is required for correct folding
Protein Eng. 1998 11: 1267-1276; doi:10.1093/protein/11.12.1267 [Abstract] [PDF] [Request Permissions]  

M Wang, LS Lee, A Nepomich, JD Yang, C Conover, M Whitlow, and D Filpula

Single-chain Fv with manifold N-glycans as bifunctional scaffolds for immunomolecules
Protein Eng. 1998 11: 1277-1283; doi:10.1093/protein/11.12.1277 [Abstract] [PDF] [Request Permissions]  

K Psarras, M Ueda, T Yamamura, S Ozawa, M Kitajima, S Aiso, S Komatsu, and M Seno

Human pancreatic RNase1-human epidermal growth factor fusion: an entirely human 'immunotoxin analog' with cytotoxic properties against squamous cell carcinomas
Protein Eng. 1998 11: 1285-1292; doi:10.1093/protein/11.12.1285 [Abstract] [PDF] [Request Permissions]  

Y Kawata, K Hongo, T Mizobata, and J Nagai

Chaperonin GroE-facilitated refolding of disulfide-bonded and reduced Taka-amylase A from Aspergillus oryzae
Protein Eng. 1998 11: 1293-1298; doi:10.1093/protein/11.12.1293 [Abstract] [PDF] [Request Permissions]  

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