Protein Engineering Design and Selection

ORIGINAL ARTICLE:

R.K. Singh, S. Gourinath, S. Sharma, I. Roy, M.N. Gupta, Ch. Betzel, A. Srinivasan, and T.P. Singh

Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 Å resolution
Protein Eng. 2001 14: 307-313; doi:10.1093/protein/14.5.307 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

William Parker, Annu Sood, and Alice Song

Organization of regions with amphiphilic -helical potential within the three-dimensional structure of ß-sheet proteins
Protein Eng. 2001 14: 315-319; doi:10.1093/protein/14.5.315 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Vasiliki E. Fadouloglou, Nicholas M. Glykos, and Michael Kokkinidis

Side-chain conformations in 4--helical bundles
Protein Eng. 2001 14: 321-328; doi:10.1093/protein/14.5.321 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rainer König and Thomas Dandekar

Solvent entropy-driven searching for protein modeling examined and tested in simplified models
Protein Eng. 2001 14: 329-335; doi:10.1093/protein/14.5.329 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Daniel Bur, Glenn E. Dale, and Christian Oefner

A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP)
Protein Eng. 2001 14: 337-341; doi:10.1093/protein/14.5.337 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yun Ho Kim, April H. Berry, Daniel S. Spencer, and Wesley E. Stites

Comparing the effect on protein stability of methionine oxidation versus mutagenesis: steps toward engineering oxidative resistance in proteins
Protein Eng. 2001 14: 343-347; doi:10.1093/protein/14.5.343 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Ravichandran, J. Dasgupta, C. Chakrabarti, S. Ghosh, M. Singh, and J.K. Dattagupta

The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14Lys and Asn14Asp
Protein Eng. 2001 14: 349-357; doi:10.1093/protein/14.5.349 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Belur N. Manjula, Ashok Malavalli, Muthuchidambaram Prabhakaran, Joel M. Friedman, and A.Seetharama Acharya

Activation of the low oxygen affinity-inducing potential of the Asn108(ß)Lys mutation of Hb-Presbyterian on intramolecular -fumaryl cross-bridging
Protein Eng. 2001 14: 359-366; doi:10.1093/protein/14.5.359 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brian C. Tripp, Zhijian Lu, Karen Bourque, Hemchand Sookdeo, and John M. McCoy

Investigation of the `switch-epitope' concept with random peptide libraries displayed as thioredoxin loop fusions
Protein Eng. 2001 14: 367-377; doi:10.1093/protein/14.5.367 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Becerra, S.Díaz Prado, M.I.González Siso, and M.E. Cerdán

New secretory strategies for Kluyveromyces lactis ß-galactosidase
Protein Eng. 2001 14: 379-386; doi:10.1093/protein/14.5.379 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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