Cover design Surface maps of the anti-microbial 18 amino acid peptides ovispirin-1 (parent peptide; left), novispirin-10 (centre) and novispirin T-7 (right) conformers. Lipophobic areas are blue, while lipophilic areas are reddish-brown. While ovispirin-1 is highly toxic to mammalian cells, the two mutant peptides have a considerably reduced toxicity whilst retaining their anti-microbial activity. For further details see Sawai,
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