Protein Engineering Design and Selection

EDITORIALS:

Welcome to Protein Engineering, Design and Selection
Protein Engineering, Design and Selection 2004 17: 1; doi:10.1093/protein/gzh008 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Helen M. Cohen, Dan S. Tawfik, and Andrew D. Griffiths

Altering the sequence specificity of HaeIII methyltransferase by directed evolution using in vitro compartmentalization
Protein Engineering, Design and Selection 2004 17: 3-11; doi:10.1093/protein/gzh001 [Abstract] [FREE Full Text] [PDF] Supplementary data [Request Permissions]  

Nicolas Fischer, Lutz Riechmann, and Greg Winter

A native-like artificial protein from antisense DNA
Protein Engineering, Design and Selection 2004 17: 13-20; doi:10.1093/protein/gzh002 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tove Olafsen, Chia-wei Cheung, Paul J. Yazaki, Lin Li, Gobalakrishnan Sundaresan, Sanjiv S. Gambhir, Mark A. Sherman, Lawrence E. Williams, John E. Shively, Andrew A. Raubitschek, and Anna M. Wu

Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications
Protein Engineering, Design and Selection 2004 17: 21-27; doi:10.1093/protein/gzh009 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Cezary Czaplewski, Stanislaw Oldziej, Adam Liwo, and Harold A. Scheraga

Prediction of the structures of proteins with the UNRES force field, including dynamic formation and breaking of disulfide bonds
Protein Engineering, Design and Selection 2004 17: 29-36; doi:10.1093/protein/gzh003 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David Ott, Renato Frischknecht, and Andreas Plückthun

Construction and characterization of a kappa opioid receptor devoid of all free cysteines
Protein Engineering, Design and Selection 2004 17: 37-48; doi:10.1093/protein/gzh004 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anna-Karin Larsson, Lars O. Emrén, William G. Bardsley, and Bengt Mannervik

Directed enzyme evolution guided by multidimensional analysis of substrate-activity space
Protein Engineering, Design and Selection 2004 17: 49-55; doi:10.1093/protein/gzh005 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. Trabbic-Carlson, D.E. Meyer, L. Liu, R. Piervincenzi, N. Nath, T. LaBean, and A. Chilkoti

Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity?
Protein Engineering, Design and Selection 2004 17: 57-66; doi:10.1093/protein/gzh006 [Abstract] [FREE Full Text] [PDF] Supplementary data [Request Permissions]  

Yinan Wei and Michael H. Hecht

Enzyme-like proteins from an unselected library of designed amino acid sequences
Protein Engineering, Design and Selection 2004 17: 67-75; doi:10.1093/protein/gzh007 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Thomas J. Magliery and Lynne Regan

A cell-based screen for function of the four-helix bundle protein Rop: a new tool for combinatorial experiments in biophysics
Protein Engineering, Design and Selection 2004 17: 77-83; doi:10.1093/protein/gzh010 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sergey P. Martsev, Yaroslav I. Tsybovsky, Oleg A. Stremovskiy, Sergey G. Odintsov, Taras G. Balandin, Paolo Arosio, Zinaida I. Kravchuk, and Sergey M. Deyev

Fusion of the antiferritin antibody VL domain to barnase results in enhanced solubility and altered pH stability
Protein Engineering, Design and Selection 2004 17: 85-93; doi:10.1093/protein/gzh011 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Zoey L. Fredericks, Carla Forte, Irene V. Capuano, Hongxing Zhou, Tim Vanden Bos, and Paul Carter

Identification of potent human anti-IL-1R_I antagonist antibodies
Protein Engineering, Design and Selection 2004 17: 95-106; doi:10.1093/protein/gzh012 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter Duckert, Søren Brunak, and Nikolaj Blom

Prediction of proprotein convertase cleavage sites
Protein Engineering, Design and Selection 2004 17: 107-112; doi:10.1093/protein/gzh013 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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