Cover.
Savinase is shown in cartoon style using PyMOL (DeLano, The PyMOL Molecular Graphics System. DeLano Scientics LLC, San Carlos, CA. http://www.pymol.org, 2003). Red represents the region where H5 is different from savinase, corresponding to V104S, L124M (front left and deep in the binding site, respectively), P129S, S130G, P131E (the binding loop), AL133S, T134L and L135I (red region at the end of the α-helix). The binding region is seen to the left of the red loop. The catalytic triad is indicated with yellow sticks (D32, H64 and S221) and is placed right over the binding region and on the lower left side of the central α-helix. For further details, see Tindbaek et al., pages 149–156.
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