cover illustration The most frequent motif in the structurally characterized leucine-rich nuclear export signals is an amphipathic α-helix.The figure shows a structural alignment of six α-helical nuclear export signals, with the regularly interspaced hydrophobic residues and a conserved acidic residue shown in balland- stick representation.The helices are coloured blue at the N-terminus. For further details, see la Cour et al pages 527-536.
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