cover illustration Molecular modelling of the TCCR construct expressing the C-terminus of HIV-1 reverse transcriptase p66 and p51 subunits as a single polypeptide with RNase H activity.The linker region connecting p66 and P51 consists of two loop regions surrounding sequences from the HIV-1 thumb.The subdomains of p66 and p51 are coloured: p66 thumb (T), dark blue; p66 connection (C), light orange; RNase H (R), green; p51 thumb (T), turquoise; p51 connection (C), red; synthetic linker, pink.The figure was generated in MOLSCRIPT 2.1 by Marie Coté based on 1RTJ. For further details, see Zúñiga et al pages 581-587.
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