Protein Engineering Design and Selection

ORIGINAL ARTICLES:

Allen Nguyen, Arthur E. Reyes, II, Min Zhang, Paul McDonald, Wai Lee T. Wong, Lisa A. Damico, and Mark S. Dennis

The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin
PEDS Advance Access published on April 18, 2006
Protein Engineering, Design and Selection 2006 19: 291-297; doi:10.1093/protein/gzl011 [Abstract] [Full Text] [PDF] [Request Permissions]  

Charlotte F. McDonagh, Eileen Turcott, Lori Westendorf, Jennifer B. Webster, Stephen C. Alley, Kristine Kim, Jamie Andreyka, Ivan Stone, Kevin J. Hamblett, Joseph A. Francisco, and Paul Carter

Engineered antibody–drug conjugates with defined sites and stoichiometries of drug attachment
PEDS Advance Access published on April 27, 2006
Protein Engineering, Design and Selection 2006 19: 299-307; doi:10.1093/protein/gzl013 [Abstract] [Full Text] [PDF] [Request Permissions]  

Thomas Gronemeyer, Christopher Chidley, Alexandre Juillerat, Christian Heinis, and Kai Johnsson

Directed evolution of O⁶-alkylguanine-DNA alkyltransferase for applications in protein labeling
PEDS Advance Access published on April 25, 2006
Protein Engineering, Design and Selection 2006 19: 309-316; doi:10.1093/protein/gzl014 [Abstract] [Full Text] [PDF] [Request Permissions]  

Carl Reid, Mia Rushe, Matthew Jarpe, Herman van Vlijmen, Brian Dolinski, Fang Qian, Teresa G. Cachero, Hernan Cuervo, Milka Yanachkova, Chioma Nwankwo, Xin Wang, Natalie Etienne, Ellen Garber, Véronique Bailly, Antonin de Fougerolles, and P.Ann Boriack-Sjodin

Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody
PEDS Advance Access published on May 8, 2006
Protein Engineering, Design and Selection 2006 19: 317-324; doi:10.1093/protein/gzl015 [Abstract] [Full Text] [PDF] supplementary data [Request Permissions]  

Stephen J. Demarest, Gang Chen, Bruce E. Kimmel, David Gustafson, Jane Wu, Jared Salbato, John Poland, Marikka Elia, Xuqiu Tan, Ken Wong, Jay Short, and Geneviève Hansen

Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression
PEDS Advance Access published on May 3, 2006
Protein Engineering, Design and Selection 2006 19: 325-336; doi:10.1093/protein/gzl016 [Abstract] [Full Text] [PDF] [Request Permissions]  

C. Angkawidjaja, K. Kuwahara, K. Omori, Y. Koga, K. Takano, and S. Kanaya

Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization
PEDS Advance Access published on May 19, 2006
Protein Engineering, Design and Selection 2006 19: 337-343; doi:10.1093/protein/gzl017 [Abstract] [Full Text] [PDF] [Request Permissions]  

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