Protein Engineering Design and Selection

ORIGINAL ARTICLES:

Martin Vingron and Patrick Argos

Determination of reliable regions in protein sequence alignments
Protein Eng. 1990 3: 565-569; doi:10.1093/protein/3.7.565 [Abstract] [PDF] [Request Permissions]  

Nobumitsu Hanioka, Kenneth Korzekwa, and Frank J. Gonzalez

Sequence requirements for cytochromes P450IIA1 and P450IIA2 catalytic activity: evidence for both specific and non-specific substrate binding interactions through use of chimeric cDNAs and cDNA expression
Protein Eng. 1990 3: 571-575; doi:10.1093/protein/3.7.571 [Abstract] [PDF] [Request Permissions]  

Fariba Fischel-Ghodsian, George Mathiowitz, and Temple F. Smith

Alignment of protein sequences using secondary structure: a modified dynamic programming method
Protein Eng. 1990 3: 577-581; doi:10.1093/protein/3.7.577 [Abstract] [PDF] [Request Permissions]  

Z.-B. Xu, C.-H. Chang, and M. Schiffer

Testing the procedure of simulated annealing by refining homologous immunoglobulin light-chain dimers
Protein Eng. 1990 3: 583-589; doi:10.1093/protein/3.7.583 [Abstract] [PDF] [Request Permissions]  

Charles Eigenbrot, Michael Randal, and Anthony A. Kossiakoff

Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 Å
Protein Eng. 1990 3: 591-598; doi:10.1093/protein/3.7.591 [Abstract] [PDF] [Request Permissions]  

Oscar P. Kuipers, Jana Kerver, Joop van Meersbergen, Roel Vis, Ruud Dijkman, Hubertus M. Verheij, and Gerard H. de Haas

Influence of size and polarity of residue 31 in porcine pancreatic phospholipase A₂ on catalytic properties
Protein Eng. 1990 3: 599-603; doi:10.1093/protein/3.7.599 [Abstract] [PDF] [Request Permissions]  

Dimitris Mantafounis and Jim Pitts

Protein engineering of chymosin; modification of the optimum pH of enzyme catalysis
Protein Eng. 1990 3: 605-609; doi:10.1093/protein/3.7.605 [Abstract] [PDF] [Request Permissions]  

Ronald Wetzel, L. Jeanne Perry, Constance Veilleux, and Gregory Chang

Mutational analysis of the C-terminus of human interferon-
Protein Eng. 1990 3: 611-623; doi:10.1093/protein/3.7.611 [Abstract] [PDF] [Request Permissions]  

Antoni Planas and Jack F. Kirsch

Sequential protection–modification method for selective sulfhydryl group derivatization in proteins having more than one cysteine
Protein Eng. 1990 3: 625-628; doi:10.1093/protein/3.7.625 [Abstract] [PDF] [Request Permissions]  

Pierre Meulien, Alain Balland, Pierre Lepage, Fabienne Mischler, Karin Dott, Catherine Hauss, Michel Grandgeorge, and Jean-Pierre Lecocq

Increased biological activity of a recombinant factor IX variant carrying alanine at position +1
Protein Eng. 1990 3: 629-633; doi:10.1093/protein/3.7.629 [Abstract] [PDF] [Request Permissions]  

P.D. Hunt, S.P. Tolley, R.J. Ward, C.P. Hill, and G.G. Dodson

Expression, purification and crystallization of penicillin G acylase from Escherichia coli ATCC 11105
Protein Eng. 1990 3: 635-639; doi:10.1093/protein/3.7.635 [Abstract] [PDF] [Request Permissions]  

Helen Field, G.T. Yarranton, and A.R. Rees

Expression of mouse immunoglobulin light and heavy chain variable regions in Escherichia coli and reconstitution of antigen-binding activity
Protein Eng. 1990 3: 641-647; doi:10.1093/protein/3.7.641 [Abstract] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.