Protein Engineering Design and Selection

ORIGINAL ARTICLES:

L. Chiche, A. Heitz, A. Padilla, D. Le-Nguyen, and B. Castro

Solution conformation of a synthetic bis-headed inhibitor of trypsin and carboxypeptidase A: new structural alignment between the squash inhibitors and the potato carboxypeptidase inhibitor
Protein Eng. 1993 6: 675-682; doi:10.1093/protein/6.7.675 [Abstract] [PDF] [Request Permissions]  

Lachlan H. Bell, John R. Coggins, and E. James Milner-White

Mix'n'Match: an improved multiple sequence alignment procedure for distantly related proteins using secondary structure predictions, designed to be independent of the choice of gap penalty and scoring matrix
Protein Eng. 1993 6: 683-690; doi:10.1093/protein/6.7.683 [Abstract] [PDF] [Request Permissions]  

Ingebrigt Sylte, Øyvind Edvardsen, and Svein G. Dahl

Molecular dynamics of the 5-HT_1a receptor and ligands
Protein Eng. 1993 6: 691-700; doi:10.1093/protein/6.7.691 [Abstract] [PDF] [Request Permissions]  

Darin S. Katz and David W. Christianson

Modeling the uncleaved serpin antichymotrypsin and its chymotrypsin complex
Protein Eng. 1993 6: 701-709; doi:10.1093/protein/6.7.701 [Abstract] [PDF] [Request Permissions]  

Mark B. Swindells and Janet M. Thornton

A study of structural determinants in the interleukin-1 fold
Protein Eng. 1993 6: 711-715; doi:10.1093/protein/6.7.711 [Abstract] [PDF] [Request Permissions]  

Ignace Lasters and Johan Desmet

The fuzzy-end elimination theorem: correctly implementing the side chain placement algorithm based on the dead-end elimination theorem
Protein Eng. 1993 6: 717-722; doi:10.1093/protein/6.7.717 [Abstract] [PDF] [Request Permissions]  

Brian K. Shoichet and Irwin D. Kuntz

Matching chemistry and shape in molecular docking
Protein Eng. 1993 6: 723-732; doi:10.1093/protein/6.7.723 [Abstract] [PDF] [Request Permissions]  

Boris A. Chrunyk and Ronald Wetzel

Breakdown in the relationship between thermal and thermodynamic stability in an interleukin-1ß point mutant modified in a surface loop
Protein Eng. 1993 6: 733-738; doi:10.1093/protein/6.7.733 [Abstract] [PDF] [Request Permissions]  

Hans-Peter Grunert, Olfert Landt, Maria Zirpel-Giesebrecht, Jan Backmann, Udo Heinemann, Wolfram Saenger, and Ulrich Hahn

Trp59 to Tyr substitution enhances the catalytic activity of RNase T1 and of the Tyr to Trp variants in positions 24, 42 and 45
Protein Eng. 1993 6: 739-744; doi:10.1093/protein/6.7.739 [Abstract] [PDF] [Request Permissions]  

Grace Lee, Winnie Chan, Mark R. Hurle, Renee L. DesJarlais, Felicia Watson, Ganesh M. Sathe, and Ronald Wetzel

Strong inhibition of fibrinogen binding to platelet receptor _IIbß₃ by RGD sequences installed into a presentation scaffold
Protein Eng. 1993 6: 745-754; doi:10.1093/protein/6.7.745 [Abstract] [PDF] [Request Permissions]  

Aihua Pan, Feng Tie, Meizhu Yang, Jingchu Luo, Zhengxing Wang, Xiang Ding, Lingyuan Li, Zhangliang Chen, and Binggen Ru

Construction of multiple copy of -domain gene fragment of human liver metallothionein I_A in tandem arrays and its expression in transgenic tobacco plants
Protein Eng. 1993 6: 755-762; doi:10.1093/protein/6.7.755 [Abstract] [PDF] [Request Permissions]  

Guus Simons, Wim van den Heuvel, Theo Reynen, Adri Frijters, Ger Rutten, Charles J. Slangen, Martien Groenen, Willem M. de Vos, and Roland J. Siezen

Overproduction of bovine ß-casein in Escherichia coli and engineering of its main chymosin cleavage site
Protein Eng. 1993 6: 763-770; doi:10.1093/protein/6.7.763 [Abstract] [PDF] [Request Permissions]  

Friedrich W. Herberg, Sean M. Bell, and Susan S. Taylor

Expression of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli: multiple isozymes reflect different phosphorylation states
Protein Eng. 1993 6: 771-777; doi:10.1093/protein/6.7.771 [Abstract] [PDF] [Request Permissions]  

Elizabeth E Boeggeman, Petety V Balaji, Navin Sethi, Arni S Masibay, and Pradman K Qasba

Expression of deletion constructs of bovine ß-1, 4-galactosyltransferase in Escherichia coli: importance of Cysl34 for its activity
Protein Eng. 1993 6: 779-785; doi:10.1093/protein/6.7.779 [Abstract] [PDF] [Request Permissions]  

Z. Assouline, H. Shen, D.G. Kilburn, and R.A.J. Warren

Production and properties of a factor X–cellulose-binding domain fusion protein
Protein Eng. 1993 6: 787-792; doi:10.1093/protein/6.7.787 [Abstract] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.