Protein Engineering Design and Selection

ORIGINAL ARTICLES:

E.I. Shakhnovich and A.M. Gutin

A new approach to the design of stable proteins
Protein Eng. 1993 6: 793-800; doi:10.1093/protein/6.8.793 [Abstract] [PDF] [Request Permissions]  

Adam Godzik, Jeffrey Skolnick, and Andrzej Kolinski

Regularities in interaction patterns of globular proteins
Protein Eng. 1993 6: 801-810; doi:10.1093/protein/6.8.801 [Abstract] [PDF] [Request Permissions]  

Ken Nishikawa and YO Matsuo

Development of pswudoenergy potentials for assessing protein 3-D-1-D compatibility and detecting weak homologies
Protein Eng. 1993 6: 811-820; doi:10.1093/protein/6.8.811 [Abstract] [PDF] [Request Permissions]  

Jérôme Gracy, Laurent Chiche, and Jean Sallantin

Improved alignment of weakly homologous protein sequences using structural information
Protein Eng. 1993 6: 821-829; doi:10.1093/protein/6.8.821 [Abstract] [PDF] [Request Permissions]  

Burkhard Rost and Chris sander

Secondary structure prediction of all-helical proteins in two states
Protein Eng. 1993 6: 831-836; doi:10.1093/protein/6.8.831 [Abstract] [PDF] [Request Permissions]  

Usha Rao and Martha M. Teeter

Improvement of turn structure prediction by molecular dynamics: a case study of ₁-purothionin
Protein Eng. 1993 6: 837-847; doi:10.1093/protein/6.8.837 [Abstract] [PDF] [Request Permissions]  

Jonathan M. Levin, Stefano Pascarella, Patrick Argos, and Jean Garnier

Quantification of secondary structure prediction improvement using multiple alignments
Protein Eng. 1993 6: 849-854; doi:10.1093/protein/6.8.849 [Abstract] [PDF] [Request Permissions]  

Matin Norin, Ole Olsen, Allan Svendsen, Olle Edholm, and Karl Hult

Theoretical studies of Rhizomucor miehei lipase activation
Protein Eng. 1993 6: 855-863; doi:10.1093/protein/6.8.855 [Abstract] [PDF] [Request Permissions]  

Thomas J. Oldfield, Peter Murray-Rust, and Roderick E. Hubbard

Model structures and action of interleukin 1 and its antagonist
Protein Eng. 1993 6: 865-871; doi:10.1093/protein/6.8.865 [Abstract] [PDF] [Request Permissions]  

R. Sowdhamini, C. Ramakrishnan, and P. Balaram

Modelling multiple disulphide loop containing polypeptides by random conformation generation. The test cases of -conotoxin GI and edothelin I
Protein Eng. 1993 6: 873-882; doi:10.1093/protein/6.8.873 [Abstract] [PDF] [Request Permissions]  

P. Pushko, T. Kozlovskaya, I. Sominskaya, A. Brede, E. Stankevica, V. Ose, P. Pumpens, and E. Grens

Analysis of RNA phage fr coat protein assembly by insertion, deletion and substitution mutagenesis
Protein Eng. 1993 6: 883-891; doi:10.1093/protein/6.8.883 [Abstract] [PDF] [Request Permissions]  

Véronique Mainfroid, Karine Goraj, Francoise Rentier-Delrue, Annick Houbrechts, Martin E.M. Noble, Torben V. Borchert, Rik K. Wierenga, and Joseph A. Martial

Replacing the (ß)-unit 8 of E.coli TIM with its chicken homologue leads to a stable and active hybrid enzyme
Protein Eng. 1993 6: 893-900; doi:10.1093/protein/6.8.893 [Abstract] [PDF] [Request Permissions]  

A. Tarragona-Fiol, H.J. Eggelte, S. Harbron, E. Sanchez, C.J. Taylorson, J.M. Ward, and B.R. Rabin

Identification by site-directed mutagenesis of amino acids in the subsite of bovine pancreatic ribonuclease A
Protein Eng. 1993 6: 901-906; doi:10.1093/protein/6.8.901 [Abstract] [PDF] [Request Permissions]  

Helèn Carlsson, Virapong Prachayasittikul, and Leif BÜlow

Zinc ions bound to chimeric His₄/lactate dehydrogenase facilitate decarboxylation of oxaloacetate
Protein Eng. 1993 6: 907-911; doi:10.1093/protein/6.8.907 [Abstract] [PDF] [Request Permissions]  

Ellen Witt, Rainer Frank, and Wolfgang Hengstenberg

6-Phospho-ß-galactosidases of Gram-positive and 6-phospho-ß-glucosidase B of Gram-negative bacteria: comparison of structure and function by kinetic and immunological methods and mutagenesis of the lacG gene of staphylococcus aureus
Protein Eng. 1993 6: 913-920; doi:10.1093/protein/6.8.913 [Abstract] [PDF] [Request Permissions]  

Jae-Seon Park, Jun Hitomi, Sueharu Horinouchi, and Teruhiko Beppu

Identification of two amino acids contributing the high enzyme activity in the alkaline pH range of an alkaline endoglucanase from a Bacillus sP
Protein Eng. 1993 6: 921-926; doi:10.1093/protein/6.8.921 [Abstract] [PDF] [Request Permissions]  

Roland J. Siezen, Paul G. Bruinenberg, Pieter Vos, Ingrid Van Alen-Boerrigter, Monique Nijhuis, Arno C. Alting, Fred A. Exterkate, and Willem M.de Vos

Engineering of the substrate-binding region of the sublilisin-like, cell-envelop proteinase of Lactococcus lactis
Protein Eng. 1993 6: 927-937; doi:10.1093/protein/6.8.927 [Abstract] [PDF] [Request Permissions]  

Ufuk Bakir, Pedro M. Coutinho, Patrick A. Sullivan, Clark Ford, and Peter J. Reilly

Cassette mutagenesis of Aspergillus awamori glucoamylase near its general acid residue to probe its catalytic and pH properties
Protein Eng. 1993 6: 939-946; doi:10.1093/protein/6.8.939 [Abstract] [PDF] [Request Permissions]  

K. Tokatlidis, P. Dhurjati, and P. Béguin

Properties conferred on Clostridium thermocellum endoglucanase CelC by grafting the duplicated segment of endoglucanase CelD
Protein Eng. 1993 6: 947-952; doi:10.1093/protein/6.8.947 [Abstract] [PDF] [Request Permissions]  

Roger Hewson, Richard J. Newbold, and David Whitford

The expression of bovine microsomal cytochrome b₅ in Escherichia coli and a study of the solution structure and stability of variant proteins
Protein Eng. 1993 6: 953-964; doi:10.1093/protein/6.8.953 [Abstract] [PDF] [Request Permissions]  

Fiona Gray, Jason G. Cyster, Antony C. Willis, A.Neil Barclay, and Alan F. Williams

Structural analysis of the CD2 T lymphocyte antigen by site-directed mutagenesis to introduce a disulphide bond into domain 1
Protein Eng. 1993 6: 965-970; doi:10.1093/protein/6.8.965 [Abstract] [PDF] [Request Permissions]  

Frank Kolbinger, José Saldanha, Norman Hardman, and Mary M. Bendig

Humanization of a mouse anti-human IgE antibody: a potential therapeutic for IgE-mediated allergies
Protein Eng. 1993 6: 971-980; doi:10.1093/protein/6.8.971 [Abstract] [PDF] [Request Permissions]  

Vernon K. Ward, Peter G. Sehneider, Sabine B. Kreissig, Bruce D. Hammock, and Prabhakara V. Choudary

Cloning, sequencing and expression of the Fab fragment of a monoclonal antibody to the herbicide atrazine
Protein Eng. 1993 6: 981-988; doi:10.1093/protein/6.8.981 [Abstract] [PDF] [Request Permissions]  

Mare Whitlow, Brian A. Bell, Sheau-Line Feng, David Filpula, Karl D. Hardman, Steven L. Hubert, Michele L. Rollence, James F. Wood, Margaret E. Schott, Diane E. Milenic, Takashi Yokota, and Jeffrey Schlom

An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability
Protein Eng. 1993 6: 989-995; doi:10.1093/protein/6.8.989 [Abstract] [PDF] [Request Permissions]  

Alexey M. Eroshkin, Peter A. Zhilkin, Vladimir V. Shamin, Sergey Korolev, and Boris B. Fedorov

Artificial protein vaccines with predetermined tertiary structure: application to anti-HTV-1 vaccine design
Protein Eng. 1993 6: 997-1001; doi:10.1093/protein/6.8.997 [Abstract] [PDF] [Request Permissions]  

Abstracts of the 5th Annual Meeting of the Protein Engineering Society of Japan
Protein Eng. 1993 6: 1003-1029; doi:10.1093/protein/6.8.1003 [PDF] [Request Permissions]  

Acknowledgements:

Acknowledgements
Protein Eng. 1993 6: 1031; doi:10.1093/protein/6.8.1031 [PDF] [Request Permissions]  

Volume contents:

Volume Contents
Protein Eng. 1993 6: 1033-1039; doi:10.1093/protein/6.8.1033 [PDF] [Request Permissions]  

Author index:

Author index
Protein Eng. 1993 6: 1041-1042; doi:10.1093/protein/6.8.1041 [PDF] [Request Permissions]  

Subject index:

Subject index
Protein Eng. 1993 6: 1043-1047; doi:10.1093/protein/6.8.1043 [PDF] [Request Permissions]  

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