Protein Engineering Design and Selection

COMMENTARY:

Robert B. Russell

Domain insertion
Protein Eng. 1994 7: 1407-1410; doi:10.1093/protein/7.12.1407 [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

David P. Hearst and Fred E. Cohensup

GRAFTER: a computational aid for the design of novel proteins
Protein Eng. 1994 7: 1411-1421; doi:10.1093/protein/7.12.1411 [Abstract] [PDF] [Request Permissions]  

L. Cardle and M.J. Dufton

Identification of important functional environs in protein tertiary structures from the analysis of residue variation in 3-D: application to cytochromes c and carboxypeptidases A and B
Protein Eng. 1994 7: 1423-1431; doi:10.1093/protein/7.12.1423 [Abstract] [PDF] [Request Permissions]  

Katsuhisa Horimoto, Hisanori Yamamoto, Kazuo Yanagi, Kunio Ohshima, and Jinya Otsuka

A simple procedure for assigning a sequence motif with an obscure pattern: application to the basic/helix-loop-helix motif
Protein Eng. 1994 7: 1433-1440; doi:10.1093/protein/7.12.1433 [Abstract] [PDF] [Request Permissions]  

Xincal Luo, Daqun Zhang, and Harel Weinstein

Ligand-induced domain motion in the activation mechanism of a G-protein-coupled receptor
Protein Eng. 1994 7: 1441-1448; doi:10.1093/protein/7.12.1441 [Abstract] [PDF] [Request Permissions]  

Liisa Holm, Chris Sander, Heinz Rüterjans, Manfred Schnarr, Rasmus Fogh, Rolf Boelens, and Robert Kaptein

LexA repressor and iron uptake regulator from Escherichia coli: new members of the CAP-like DNA binding domain superfamily
Protein Eng. 1994 7: 1449-1453; doi:10.1093/protein/7.12.1449 [Abstract] [PDF] [Request Permissions]  

M.T. Pisabarro, A.R. Ortiz, A.R. Viguera, F. Gago, and L. Serrano

Molecular modeling of the interaction of polyproline-based peptides with the Abl-SH3 domain: rational modification of the interaction
Protein Eng. 1994 7: 1455-1462; doi:10.1093/protein/7.12.1455 [Abstract] [PDF] [Request Permissions]  

Stephen P. Bottomley, Andrew G. Popplewell, Michael Scawen, Tommy Wan, Brian J. Sutton, and Michael G. Gore

The stability and unfolding of an IgG binding protein based upon the B domain of protein A from Staphylococcus aureus probed by tryptophan substitution and fluorescence spectroscopy
Protein Eng. 1994 7: 1463-1470; doi:10.1093/protein/7.12.1463 [Abstract] [PDF] [Request Permissions]  

Andrea Tomschy, Gerald Bohm, and Rainer Jaenicke

The effect of ion pairs on the thermal stability of D-glyceraldehyde 3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima
Protein Eng. 1994 7: 1471-1478; doi:10.1093/protein/7.12.1471 [Abstract] [PDF] [Request Permissions]  

Michael R. Sierks and Blrte Svensson

Protein engineering of the relative specificity of glucoamylase from Aspergillus awamori based on sequence similarities between starch-degrading enzymes
Protein Eng. 1994 7: 1479-1484; doi:10.1093/protein/7.12.1479 [Abstract] [PDF] [Request Permissions]  

A. Gururaj Rao, Moises Hassan, and C. Hemple

Structure-function validation of high lysine analogs of -hordothionin designed by protein modeling
Protein Eng. 1994 7: 1485-1493; doi:10.1093/protein/7.12.1485 [Abstract] [PDF] [Request Permissions]  

Jacques Izard, Michael W. Parker, Martlne Chartier, Denis Ducheé, and Daniel Baty

A single amino acid substitution can restore the solubility of aggregated colicin A mutants in Escherichia coli
Protein Eng. 1994 7: 1495-1500; doi:10.1093/protein/7.12.1495 [Abstract] [PDF] [Request Permissions]  

Philip R. Tempest, Patricia White, E.Diane Williamson, Richard W. Titball, David C. Kelly, Graham J.L. Kemp, Peter M.D. Gray, Simon J. Forster, Frank J. Carr, and William J. Harris

Efficient generation of a reshaped human mAb specific for the toxin of Clostridium perfringens
Protein Eng. 1994 7: 1501-1507; doi:10.1093/protein/7.12.1501 [Abstract] [PDF] [Request Permissions]  

Itai Benhar and Ira Pastan

Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs Bl and B5 as single-chain immunotoxins
Protein Eng. 1994 7: 1509-1515; doi:10.1093/protein/7.12.1509 [Abstract] [PDF] [Request Permissions]  

Acknowledgements:

Acknowledgements
Protein Eng. 1994 7: 1517-1518; doi:10.1093/protein/7.12.1517 [PDF] [Request Permissions]  

Author index:

Author index
Protein Eng. 1994 7: 1519-1521; doi:10.1093/protein/7.12.1519 [PDF] [Request Permissions]  

Subject index:

Subject index
Protein Eng. 1994 7: 1523-1529; doi:10.1093/protein/7.12.1523 [PDF] [Request Permissions]  

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