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Previous 		Contents: Volume 23, Number 4, April 2010   [Index by Author] 

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Editorial Back

Janice M. Reichert
Editorial for PEDS special issue on antibodies
Protein Engineering, Design and Selection 2010 23: 153-154; doi:10.1093/protein/gzq018 [Extract] [Full Text] [PDF] [Request Permissions]  

Short communications Back

Lorenzo Benatuil, Jennifer M. Perez, Jonathan Belk, and Chung-Ming Hsieh
An improved yeast transformation method for the generation of very large human antibody libraries
PEDS Advance Access published on February 3, 2010
Protein Engineering, Design and Selection 2010 23: 155-159; doi:10.1093/protein/gzq002 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Lars Friedrich, Stefan Stangl, Hannes Hahne, Bernhard Küster, Peter Köhler, Gabriele Multhoff, and Arne Skerra
Bacterial production and functional characterization of the Fab fragment of the murine IgG1/{lambda} monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics
PEDS Advance Access published on February 1, 2010
Protein Engineering, Design and Selection 2010 23: 161-168; doi:10.1093/protein/gzp095 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles Back

Marija Backovic, Daniel X. Johansson, Barbara G. Klupp, Thomas C. Mettenleiter, Mats A.A. Persson, and Felix A. Rey
Efficient method for production of high yields of Fab fragments in Drosophila S2 cells
PEDS Advance Access published on January 24, 2010
Protein Engineering, Design and Selection 2010 23: 169-174; doi:10.1093/protein/gzp088 [Abstract] [Full Text] [PDF] [Request Permissions]  

Christian Zahnd, Casim A. Sarkar, and Andreas Plückthun
Computational analysis of off-rate selection experiments to optimize affinity maturation by directed evolution
PEDS Advance Access published on February 3, 2010
Protein Engineering, Design and Selection 2010 23: 175-184; doi:10.1093/protein/gzp087 [Abstract] [Full Text] [PDF] [Request Permissions]  

Hiroto Iwai, Bengü Öztürk, Masaki Ihara, and Hiroshi Ueda
Antibody affinity maturation in vitro using unconjugated peptide antigen
PEDS Advance Access published on February 1, 2010
Protein Engineering, Design and Selection 2010 23: 185-193; doi:10.1093/protein/gzp093 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Jonathan H. Davis, Christel Aperlo, Yue Li, Emmi Kurosawa, Yan Lan, Kin-Ming Lo, and James S. Huston
SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies
PEDS Advance Access published on February 4, 2010
Protein Engineering, Design and Selection 2010 23: 195-202; doi:10.1093/protein/gzp094 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Sosthene Essono, Gilles Clément, Severine Padiolleau-Lefevre, Christophe Créminon, Jacques Grassi, and Didier Boquet
Peptide mass-assisted antibody cloning strategy for accurate characterization of potential therapeutic monoclonal antibodies against neurodegenerative diseases
PEDS Advance Access published on December 1, 2009
Protein Engineering, Design and Selection 2010 23: 203-210; doi:10.1093/protein/gzp071 [Abstract] [Full Text] [PDF] [Request Permissions]  

Benjamin J. Hackel and K. Dane Wittrup
The full amino acid repertoire is superior to serine/tyrosine for selection of high affinity immunoglobulin G binders from the fibronectin scaffold
PEDS Advance Access published on January 12, 2010
Protein Engineering, Design and Selection 2010 23: 211-219; doi:10.1093/protein/gzp083 [Abstract] [Full Text] [PDF] [Request Permissions]  

Kelly Davis Orcutt, Margaret E. Ackerman, Maryelise Cieslewicz, Emmanuel Quiroz, Adrian L. Slusarczyk, John V. Frangioni, and K. Dane Wittrup
A modular IgG-scFv bispecific antibody topology
PEDS Advance Access published on December 17, 2009
Protein Engineering, Design and Selection 2010 23: 221-228; doi:10.1093/protein/gzp077 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Elodie Brient-Litzler, Andreas Plückthun, and Hugues Bedouelle
Knowledge-based design of reagentless fluorescent biosensors from a designed ankyrin repeat protein
PEDS Advance Access published on November 27, 2009
Protein Engineering, Design and Selection 2010 23: 229-241; doi:10.1093/protein/gzp074 [Abstract] [Full Text] [PDF] [Request Permissions]  

Tove Olafsen, Shannon J. Sirk, David J. Betting, Vania E. Kenanova, Karl B. Bauer, Waldemar Ladno, Andrew A. Raubitschek, John M. Timmerman, and Anna M. Wu
ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies)
PEDS Advance Access published on January 6, 2010
Protein Engineering, Design and Selection 2010 23: 243-249; doi:10.1093/protein/gzp081 [Abstract] [Full Text] [PDF] [Request Permissions]  

Noah D. Taylor, Jeffrey C. Way, Pamela A. Silver, and Pablo Cironi
Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity
PEDS Advance Access published on January 18, 2010
Protein Engineering, Design and Selection 2010 23: 251-260; doi:10.1093/protein/gzp085 [Abstract] [Full Text] [PDF] [Request Permissions]  

David Sgier, Kathrin Zuberbuehler, Stefanie Pfaffen, and Dario Neri
Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA
PEDS Advance Access published on January 19, 2010
Protein Engineering, Design and Selection 2010 23: 261-269; doi:10.1093/protein/gzp089 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Adam Walker, Gráinne Dunlevy, Daniel Rycroft, Peter Topley, Lucy J. Holt, Tom Herbert, Marie Davies, Fiona Cook, Steve Holmes, Laurent Jespers, and Chris Herring
Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon
PEDS Advance Access published on January 21, 2010
Protein Engineering, Design and Selection 2010 23: 271-278; doi:10.1093/protein/gzp091 [Abstract] [Full Text] [PDF] [Request Permissions]  

K. Pershad, J.D. Pavlovic, S. Gräslund, P. Nilsson, K. Colwill, A. Karatt-Vellatt, D.J. Schofield, M.R. Dyson, T. Pawson, B.K. Kay, and J. McCafferty
Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display
PEDS Advance Access published on February 17, 2010
Protein Engineering, Design and Selection 2010 23: 279-288; doi:10.1093/protein/gzq003 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

G. Wozniak-Knopp, S. Bartl, A. Bauer, M. Mostageer, M. Woisetschläger, B. Antes, K. Ettl, M. Kainer, G. Weberhofer, S. Wiederkum, G. Himmler, G.C. Mudde, and F. Rüker
Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties
PEDS Advance Access published on February 11, 2010
Protein Engineering, Design and Selection 2010 23: 289-297; doi:10.1093/protein/gzq005 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Jeff L. Ellsworth, Nels Hamacher, Brandon Harder, Mark Maurer, Thomas R. Bukowski, Megan Lantry, Claire Noriega, Mark W. Rixon, Brian Fox, Ken Lewis, Brent Meengs, Emily Rollins, Karlien Greeff, Jeff Meyer, and Carl Birks
Generation of a high-affinity Fc{gamma} receptor by Ig-domain swapping between human CD64A and CD16A
PEDS Advance Access published on February 11, 2010
Protein Engineering, Design and Selection 2010 23: 299-309; doi:10.1093/protein/gzq007 [Abstract] [Full Text] [PDF] [Request Permissions]  

J. Lou, I. Geren, C. Garcia-Rodriguez, C.M. Forsyth, W. Wen, K. Knopp, J. Brown, T. Smith, L.A. Smith, and J.D. Marks
Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating
PEDS Advance Access published on February 15, 2010
Protein Engineering, Design and Selection 2010 23: 311-319; doi:10.1093/protein/gzq001 [Abstract] [Full Text] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.